In 2000 the Mission became known as Uniting Care Port Pirie Central Mission aligning with the national UnitingCare identity.

The Mission’s offices at Ward House in Ellen Street were quickly being outgrown. Several options were considered and a new site was identified at 60 Florence Street. In 2001 all programs had moved and were operating from the new premises.

In 2002 a Memorandum of Agreement was established between the four Missions in South Australia – Adelaide, Bowden, Port Adelaide and Port Pirie. Common badging and Strategic Plans were developed and in 2003 UnitingCare Port Pirie became UnitingCare Wesley Port Pirie.

The launch of the new badging of UnitingCare Wesley was held in Adelaide in October 2003 in the presence of Her Excellency the Governor of South Australia, Marjorie Jackson-Nelson. The Missions in Partnership met regularly to develop and provide mutual support in the areas of Information Technology, Business Excellence and Purchasing.

As services expanded rapidly over the country regions of Yorke Peninsula, Mid North, Far North and Eyre and Western, a more representative name of UnitingCare Wesley Country SA was adopted in 2011.

In 2012 UnitingCare Wesley Country SA celebrated 100 years of continuous service to communities ‘Caring for Country People’.